Ketamine vs. Spravato: Which is Right for You?

Ketamine and Spravato (esketamine) are two innovative treatments for treatment-resistant depression (TRD). Both medications offer rapid-acting relief for individuals who haven’t found success with traditional therapies. Let’s delve deeper into how these treatments compare and the options available at Advanced Psychiatry of Elgin.

Understanding Treatment-Resistant Depression

Treatment-resistant depression is a condition where traditional treatments like antidepressants and psychotherapy fail to provide significant relief. This can be a frustrating and debilitating experience.

Ketamine Infusion Therapy

How it works: Ketamine, a medication originally used as an anesthetic, has been found to have rapid antidepressant effects. It works by targeting specific receptors in the brain.

Administration: Ketamine is administered intravenously by a healthcare professional in a clinical setting.

Medication Dose: The dosage of ketamine is determined by your doctor and adjusted based on your individual needs.

Conditions Treated: Ketamine is primarily used for treatment-resistant depression, but it may also be beneficial for other conditions like anxiety disorders, suicidal ideation, OCD, bipolar, neuropathic pain and PTSD.

Requirements: To receive ketamine infusion therapy, you’ll typically need a referral from your primary care physician or mental health provider.

Timeline for Treatment: A typical course of ketamine infusion therapy involves multiple treatments over several weeks. 6-10 infusions over the course of 4-5 weeks followed by boosters as needed.

Cost and Insurance Coverage: Medication is not covered by insurance, cost for medication is out of pocket. However, insurance can be billed for monitoring.

Spravato (Esketamine)

How it works: Spravato is a nasal spray form of esketamine, a stereoisomer of ketamine. It works similarly to ketamine by targeting specific brain receptors.

Administration: Spravato is self-administered under the supervision of a healthcare professional in a certified clinic.

Medication Dose: The dosage of Spravato is determined by your doctor and adjusted based on your individual needs. There are 2 dosages to choose from 56 mg and 84 mg.

Conditions Treated: Spravato is primarily used for treatment-resistant depression, and major depressive disorder with acute suicidal ideation or behavior.

Requirements: To receive Spravato, you’ll need a prescription from your doctor and must be administered in a certified clinic.

Timeline for Treatment: A typical course of Spravato involves multiple treatments over several weeks. Appointment last 120 minutes.

Cost and Insurance Coverage: The cost of Spravato can vary, and insurance coverage may differ. Copays can be as low as $20 per kit. Please consult with our coordinator to find a plan  that best fits your financial needs. 

Which Treatment is Right for You?

The best treatment for you will depend on your individual circumstances, including your medical history, current medications, and the severity of your symptoms. Your mental health provider at Advanced Psychiatry of Elgin can help you determine the most appropriate treatment option.

If you’re struggling with treatment-resistant depression, don’t lose hope. Advanced Psychiatry of Elgin offers a range of innovative treatments, including ketamine, Spravato, and TMS, to help you find relief.

Please note that this information is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment.   

To learn more about ketamine and Spravato treatment options at Advanced Psychiatry of Elgin, please contact our office to schedule a consultation.